XXIII.—On aromatic nitrosamines
نویسندگان
چکیده
منابع مشابه
Nitrosamines and Aromatic Amines
A new method for the simultaneous determination of hemoglobin adducts from aromatic amines and tobacco-specific nitrosamines (TSNA) is described. After mild base-catalysed hydrolysis releasing aromatic amines and the TSNA adduct 4-hydroxy-1-(3-pyridyl)-1butanone (HPB), the extraction, cleanup, and concentration are performed by a one-step procedure using C 1 8 cartridges. Determination in the p...
متن کاملLevels of tobacco-specific nitrosamines and polycyclic aromatic hydrocarbons in mainstream smoke from different tobacco varieties.
It has been estimated that one in every five cancer deaths worldwide are related to tobacco use. According to the IARC, 10 polycyclic aromatic hydrocarbons (PAH) and 8 tobacco-specific nitrosamines (TSNA), as well as at least 45 other compounds or substances found in tobacco smoke, are potential human carcinogens. The levels of these carcinogens in contents of tobacco and smoke emissions vary b...
متن کاملNitrosamines and nitramines
2. Furthermore, NIPH was asked by Klif to evaluate existing risk estimates for Nnitrosodimethylamine (NDMA). This includes an evaluation of EPA/IRIS risk estimates for drinking water and air, and other risk estimates of this nitrosamine in Europe or Canada. Klif wanted an evaluation of the validity of the values, how they can be used, and how they should be interpreted. NIPH was also asked to c...
متن کاملFormation and Metabolism of N-Nitrosamines
The formation of nitrosamines and reactions of the first and second phase of their biotransformations were reviewed.
متن کاملRelevance of nitrosamines to human cancer.
It is now about three decades since the hepatocarcinogenic effect of N-nitrosodimethylamine (NDMA)* was demonstrated in rats (1) and the suggestion was made that N-nitrosamines can be formed following nitrosation of various amines (2). Direct proof that such nitrosation reactions can occur was provided by Ender et al. (3) who identified NDMA in nitrite preserved fish-meal, and by Sander and Sei...
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ژورنال
عنوان ژورنال: J. Chem. Soc., Trans.
سال: 1878
ISSN: 0368-1645
DOI: 10.1039/ct8783300202